Panadrex Syrup (Raspberry flavored)
Active ingredients: Each 5 ml contains:
Paracetamol 120 mg
Mode of Action:
Panadrex Syrup contains Paracetamol which belongs to a group of medicines called analgesics and antipyretics. The mechanism of action is probably similar to that of aspirin and dependent on the selective inhibition of prostaglandin synthesis.
Indications:
• Mild to moderate pain associated with toothache, headache, earache, backache, sore throat, dysmenorrhea, migraine, neuralgia, rheumatic ache, and teething pain.
• Fever associated with influenza, bacterial infection, inflammation, cold, and childhood infection like chickenpox, measles, mumps, and reactions to vaccinations.
Posology:
Children 6-12 years: 2-4 teaspoonful every 4-6 hours
Children 1-6 years: 1-2 teaspoonful every 4-6 hours
Precautions:
• Do not exceed the stated dose.
• Do not give more than 4 doses within 24 hours.
• Used with caution in patients with severe kidney or liver problems, alcoholic liver disease.
• Paracetamol overdose may cause liver failure.
• Patients should follow the advice of their doctor regarding its use in pregnancy. Available published data does not contraindicate breastfeeding.
Contraindications:
• Hypersensitivity to the active substances (paracetamol) or any of the other excipients.
• If the patient takes other paracetamol-containing products.
• Fructose intolerance.
• Babies < 2 months.
Undesirable effects:
Side effects of paracetamol are rare and usually mild, though hematological reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Skin rash and other hypersensitivity reactions occur occasionally.
Pharmacokinetic properties:
• Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract. The concentration in plasma reaches a peak in 30 to 60 minutes and the plasma half-life is 1 - 4 hours after therapeutic doses.
• Paracetamol is relatively uniformly distributed throughout most body fluids. Plasma protein binding is variable; 20 to 30% may be bound at the concentrations encountered during acute intoxication.
• Paracetamol is metabolized in the liver and excreted in the urine mainly as the glucuronide and sulphate conjugates, with about 10% as glutathione conjugates. Less than 5% is excreted as unchanged paracetamol.
Storage:
• Keep in a safe place, out of the reach and sight of children.
• Store at temperature not exceeding 25ºC, Protect from light
Shelf life:
• 3 years from the manufacturing date.
• The expiry date refers to the last day of the month.
How to use?
Children 6-12 years: 2-4 teaspoonful every 4-6 hours
Children 1-6 years: 1-2 teaspoonful every 4-6 hours
Ingredients
Paracetamol 120 mg
